On today’s episode, Kara welcomes Tyler Smith, Founder and CEO of Hundred — the innovative health platform turning personalized data into real, measurable transformation.

Tyler’s story is as compelling as it is inspiring. After discovering that his biological age was eight years older than his chronological age, he made a life-altering decision: invest in the world’s top physicians, build a private longevity lab, and completely reengineer his health. The result? He reversed his biological age by an astounding 15 years — and uncovered just how broken and inaccessible personalized health optimization has been for everyday people.
That breakthrough became the foundation for Hundred, a fully integrated health platform that merges blood work, wearables, medical history, AI, and guidance from top clinicians into a clear, evidence-based 100-day action plan. Before launching Hundred, Tyler built and sold SkySlope for a reported $80M, and he now brings that same focus, rigor, and obsession with outcomes to transforming how we approach our health.
In this episode, Tyler shares what drove him to build Hundred, the gaps he saw in traditional and DTC testing models, and why knowing your data is only half the battle — the real power lies in turning insight into action. He opens up about his own transformation, the science behind the platform, and what it takes to build a company at the intersection of longevity, technology, and human performance.
A must-listen for anyone passionate about proactive health, entrepreneurship, or building a life with intention.